Laboratory for Precision Multi-Material Additive Manufacturing for Microfluidics

The mission of the Precision Multi-Material Additive Manufacturing for Microfluidics lab of Dr. Fanzio is to pioneer innovative technological solutions for developing a high-resolution multi-material additive manufacturing technologies. This innovative approach seeks to overcome existing fabrication barriers in the creation of multi-functional 3D micro-devices, simplifying and democratizing the realization of complex and personalized microfluidic systems. Dr. Fanzio’s vision is to drive transformative progress in healthcare and food technology.

Cutting edge solutions

To this end, we are developing cutting-edge solutions, including:

• High-resolution multi-material additive manufacturing strategies: Developing both hardware and process innovations to enable the fabrication of complex, multifunctional devices at micro-scale resolution. Several techniques, such as Fused Filament Fabrication, Stereolithography, and Digital Light Processing, are employed.
• Advanced materials/resins for additive manufacturing: Creating and optimizing materials and resins tailored for multi-material applications.
• Tissue-mimicking microfluidic phantoms for imaging: Designing models that replicate physiological properties for medical imaging and research.
• 3D printing of microfluidics devices: Creating multi-material, multi-scale (nano to micro), 3D dimensional microfluidic networks that mimic physiological systems found in nature.
• Integration of multiple functionalities: Combining electrodes, sensing regions, and areas with varying flexibility into single-step fabrication processes.

Our work addresses critical barriers in healthcare by developing innovative manufacturing techniques to create precise, multifunctional biomedical systems, including tools for modelling vascular diseases such as small vessel disease and stroke. Beyond healthcare, our research also extends to food technology, enabling the development of 3D-printed food and pharmaceutical products for personalized medicine.

Want to collaborate?

We are actively seeking collaborations to expand the impact of our work and co-develop devices that address urgent medical challenges and improve quality of life. For more information, please contact Dr. Paola Fanzio at p.fanzio@tudelft.nl