Laboratory of cerebro-cerebellar communication

The brain demonstrates extraordinary capabilities in receiving diverse sensory inputs from the environment and converting them into precise motor actions. This phenomenon, termed sensorimotor processing, is critical not only for movement control but also for facilitating advanced cognitive and executive functions. Effective sensorimotor processing relies on intricate cooperation among multiple brain regions. Although extensive research has illuminated the cellular and circuit-level mechanisms within individual brain regions responsible for sensorimotor processing, the processes by which these regions collectively compute and coordinate remain largely unclear.

To gain deeper insights into this inter-regional communication, our research investigates the interactions among brain regions during various sensorimotor behaviors. We utilize a multifaceted approach that integrates anatomical mapping, behavioral analysis, pharmacological interventions, optogenetic manipulation, and both electrophysiological and optical recordings. Our primary objective is to map the anatomical and functional networks that underpin sensorimotor learning and the execution of natural behaviors. Ultimately, our work aims to clarify the complex interactions among brain regions that enable the brain's remarkable sensorimotor capacities